"Je vois la vie en rose" is a full-cast gender change. Canon male characters become female, and canon female characters become male or genderqueer. The only exceptions are real people and background military/government characters.
The CIA's Marcus MacTaggert attempts to recruit Doctor Charlotte Xavier and her sibling Raven to assist in the capture of suspected Communist Sabrina Shaw and her unusual associates. Thrilled at the thought finding of more mutants, Charlotte and Raven agree, but are soon put off by the CIA's misogynist attitude and decide to track down these other mutants by themselves. They do find more mutants, but not the ones they were expecting.
Charlotte starts to build a community of mutants but Raven finds that many of them can't even accept themselves, let alone someone who doesn't belong within familiar definitions of gender. Erika's determination to kill Shaw, Shaw's quest to recruit more mutants, and world-threatening political brinkmanship collide with deadly consequences: Charlotte, Raven and Erika must decide what kind of world it is that they want to create.